node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEJ71091.1 | adh2 | HMPREF0548_2034 | HMPREF0548_0475 | Hypothetical protein; COG: COG1956. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.764 |
EEJ71091.1 | clpC | HMPREF0548_2034 | HMPREF0548_2035 | Hypothetical protein; COG: COG1956. | ATPase family associated with various cellular activities (AAA); COG: COG0542; Belongs to the ClpA/ClpB family. | 0.524 |
EEJ71091.1 | metK | HMPREF0548_2034 | HMPREF0548_0458 | Hypothetical protein; COG: COG1956. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.936 |
EEJ71091.1 | mmuM1 | HMPREF0548_2034 | HMPREF0548_1045 | Hypothetical protein; COG: COG1956. | Homocysteine S-methyltransferase; COG: COG2040. | 0.897 |
EEJ71091.1 | mmuM2 | HMPREF0548_2034 | HMPREF0548_1073 | Hypothetical protein; COG: COG1956. | Homocysteine S-methyltransferase; COG: COG2040. | 0.897 |
EEJ71091.1 | msrA | HMPREF0548_2034 | HMPREF0548_0082 | Hypothetical protein; COG: COG1956. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.727 |
EEJ71091.1 | relA | HMPREF0548_2034 | HMPREF0548_0979 | Hypothetical protein; COG: COG1956. | RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.595 |
EEJ71091.1 | ribA | HMPREF0548_2034 | HMPREF0548_1134 | Hypothetical protein; COG: COG1956. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.899 |
adh2 | EEJ71091.1 | HMPREF0548_0475 | HMPREF0548_2034 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Hypothetical protein; COG: COG1956. | 0.764 |
adh2 | metK | HMPREF0548_0475 | HMPREF0548_0458 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.513 |
adh2 | ribA | HMPREF0548_0475 | HMPREF0548_1134 | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.458 |
clpC | EEJ71091.1 | HMPREF0548_2035 | HMPREF0548_2034 | ATPase family associated with various cellular activities (AAA); COG: COG0542; Belongs to the ClpA/ClpB family. | Hypothetical protein; COG: COG1956. | 0.524 |
metK | EEJ71091.1 | HMPREF0548_0458 | HMPREF0548_2034 | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Hypothetical protein; COG: COG1956. | 0.936 |
metK | adh2 | HMPREF0548_0458 | HMPREF0548_0475 | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Aldehyde dehydrogenase (NAD) family protein; COG: COG1012; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.513 |
metK | mmuM1 | HMPREF0548_0458 | HMPREF0548_1045 | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Homocysteine S-methyltransferase; COG: COG2040. | 0.905 |
metK | mmuM2 | HMPREF0548_0458 | HMPREF0548_1073 | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Homocysteine S-methyltransferase; COG: COG2040. | 0.905 |
metK | ribA | HMPREF0548_0458 | HMPREF0548_1134 | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.675 |
mmuM1 | EEJ71091.1 | HMPREF0548_1045 | HMPREF0548_2034 | Homocysteine S-methyltransferase; COG: COG2040. | Hypothetical protein; COG: COG1956. | 0.897 |
mmuM1 | metK | HMPREF0548_1045 | HMPREF0548_0458 | Homocysteine S-methyltransferase; COG: COG2040. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.905 |
mmuM2 | EEJ71091.1 | HMPREF0548_1073 | HMPREF0548_2034 | Homocysteine S-methyltransferase; COG: COG2040. | Hypothetical protein; COG: COG1956. | 0.897 |