STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEJ70949.1Hypothetical protein. (136 aa)    
Predicted Functional Partners:
trxB-2
Thioredoxin-disulfide reductase; COG: COG0492.
  
 0.934
EEJ70950.1
Transcriptional regulator, ArsR family; COG: COG0640.
 
   
 0.902
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 0.878
EEJ71898.1
Pyridine nucleotide-disulfide oxidoreductase; COG: COG1249.
  
 0.869
EEJ71903.1
Pyridine nucleotide-disulfide oxidoreductase; COG: COG1249.
  
 0.869
msrA
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.863
msrA-2
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.863
trxB
Thioredoxin-disulfide reductase; COG: COG0492.
  
 0.832
EEJ70945.1
Pyridine nucleotide-disulfide oxidoreductase; COG: COG0492.
  
 0.832
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.781
Your Current Organism:
Lactobacillus ultunensis
NCBI taxonomy Id: 525365
Other names: L. ultunensis DSM 16047, Lactobacillus ultunensis DSM 16047, Lactobacillus ultunensis str. DSM 16047, Lactobacillus ultunensis strain DSM 16047
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.