| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEJ70937.1 | pepQ | HMPREF0548_2200 | HMPREF0548_2199 | Putative catabolite control protein A; COG: COG1609. | Xaa-Pro dipeptidase; COG: COG0006; Belongs to the peptidase M24B family. | 0.844 |
| EEJ71178.1 | guaC | HMPREF0548_1910 | HMPREF0548_1455 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.949 |
| EEJ71178.1 | pepQ | HMPREF0548_1910 | HMPREF0548_2199 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Xaa-Pro dipeptidase; COG: COG0006; Belongs to the peptidase M24B family. | 0.682 |
| EEJ71178.1 | pepT | HMPREF0548_1910 | HMPREF0548_0062 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.587 |
| EEJ71178.1 | pepT-2 | HMPREF0548_1910 | HMPREF0548_0330 | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.587 |
| EEJ72233.1 | pepQ | HMPREF0548_0920 | HMPREF0548_2199 | Transcriptional regulator, AraC family. | Xaa-Pro dipeptidase; COG: COG0006; Belongs to the peptidase M24B family. | 0.912 |
| guaC | EEJ71178.1 | HMPREF0548_1455 | HMPREF0548_1910 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | Putative inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.949 |
| guaC | pepQ | HMPREF0548_1455 | HMPREF0548_2199 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | Xaa-Pro dipeptidase; COG: COG0006; Belongs to the peptidase M24B family. | 0.682 |
| guaC | pepT | HMPREF0548_1455 | HMPREF0548_0062 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.587 |
| guaC | pepT-2 | HMPREF0548_1455 | HMPREF0548_0330 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.587 |
| ileS | pepQ | HMPREF0548_0867 | HMPREF0548_2199 | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Xaa-Pro dipeptidase; COG: COG0006; Belongs to the peptidase M24B family. | 0.574 |
| pepN | pepO1 | HMPREF0548_1494 | HMPREF0548_0138 | Membrane alanyl aminopeptidase; COG: COG0308. | Peptidase family M13; COG: COG3590. | 0.594 |
| pepN | pepO2 | HMPREF0548_1494 | HMPREF0548_1734 | Membrane alanyl aminopeptidase; COG: COG0308. | Peptidase family M13; COG: COG3590. | 0.595 |
| pepN | pepQ | HMPREF0548_1494 | HMPREF0548_2199 | Membrane alanyl aminopeptidase; COG: COG0308. | Xaa-Pro dipeptidase; COG: COG0006; Belongs to the peptidase M24B family. | 0.552 |
| pepN | pepT | HMPREF0548_1494 | HMPREF0548_0062 | Membrane alanyl aminopeptidase; COG: COG0308. | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.651 |
| pepN | pepT-2 | HMPREF0548_1494 | HMPREF0548_0330 | Membrane alanyl aminopeptidase; COG: COG0308. | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. | 0.651 |
| pepO1 | pepN | HMPREF0548_0138 | HMPREF0548_1494 | Peptidase family M13; COG: COG3590. | Membrane alanyl aminopeptidase; COG: COG0308. | 0.594 |
| pepO1 | pepQ | HMPREF0548_0138 | HMPREF0548_2199 | Peptidase family M13; COG: COG3590. | Xaa-Pro dipeptidase; COG: COG0006; Belongs to the peptidase M24B family. | 0.594 |
| pepO2 | pepN | HMPREF0548_1734 | HMPREF0548_1494 | Peptidase family M13; COG: COG3590. | Membrane alanyl aminopeptidase; COG: COG0308. | 0.595 |
| pepO2 | pepQ | HMPREF0548_1734 | HMPREF0548_2199 | Peptidase family M13; COG: COG3590. | Xaa-Pro dipeptidase; COG: COG0006; Belongs to the peptidase M24B family. | 0.594 |