STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (288 aa)    
Predicted Functional Partners:
hom
Homoserine dehydrogenase; COG: COG0460; Pfam: PF03447,PF00742,PF01842; InterPro: IPR001342.
 
 0.999
thrC
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
 
 
 0.999
purM
Phosphoribosylformylglycinamidine cyclo-ligase; COG: COG0150; Pfam: PF00586,PF02769; InterPro: IPR004733.
 
    
 0.907
MetH
Homocysteine S-methyltransferase; COG: COG0685; Pfam: PF02574,PF02219; InterPro: IPR003726.
    
 0.895
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.849
ilvE
Branched-chain-amino-acid transaminase; COG: COG0115; Pfam: PF01063; InterPro: IPR001544.
  
 
 0.834
sdaAB
L-serine dehydratase, iron-sulfur-dependent, beta subunit; COG: COG1760; Pfam: PF03315,PF01842; InterPro: IPR004643; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.833
sdaAA
L-serine dehydratase, iron-sulfur-dependent, alpha subunit; COG: COG1760; Pfam: PF03313; InterPro: IPR004642; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.833
cysE
Serine O-acetyltransferase; COG: COG1045; Pfam: PF00132; InterPro: IPR005881.
     
 0.827
metC
Cystathionine beta-lyase; COG: COG0626; Pfam: PF01053; InterPro: IPR000277.
  
 
 0.824
Your Current Organism:
Listeria grayi
NCBI taxonomy Id: 525367
Other names: L. grayi DSM 20601, Listeria grayi ATCC 19120, Listeria grayi DSM 20601, Listeria grayi str. DSM 20601, Listeria grayi strain DSM 20601
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