STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dltD2DltD C-terminal domain protein; COG: COG3966; Pfam: PF04915,PF04918,PF04914; InterPro: IPR007002. (428 aa)    
Predicted Functional Partners:
dltB
MBOAT family protein; Could be involved in the transport of activated D-alanine through the membrane.
 
 
 0.999
dltA
D-alanine--poly(phosphoribitol) ligase, subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]
 
  
 0.996
dltC
D-alanine--poly(phosphoribitol) ligase, subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
 
  
 0.996
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
  
 0.739
plsX
Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
      
 0.727
EFI83868.1
Hypothetical protein.
     
 0.687
tagO
Glycosyltransferase, group 4 family; COG: COG0472; Pfam: PF00953; InterPro: IPR000715.
      
 0.685
FmtA_2
Beta-lactamase; Pfam: PF00144; InterPro: IPR001466.
 
  
 0.577
pbpX
Beta-lactamase; COG: COG1680; Pfam: PF00144; InterPro: IPR001466.
  
 0.532
EFI83170.1
Hypothetical protein; COG: COG4814; Pfam: PF06028; InterPro: IPR010315.
 
     0.531
Your Current Organism:
Listeria grayi
NCBI taxonomy Id: 525367
Other names: L. grayi DSM 20601, Listeria grayi ATCC 19120, Listeria grayi DSM 20601, Listeria grayi str. DSM 20601, Listeria grayi strain DSM 20601
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