node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFI83635.1 | UbiG | HMPREF0556_12320 | HMPREF0556_12322 | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | 0.657 |
EFI83635.1 | aroE | HMPREF0556_12320 | HMPREF0556_12317 | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.873 |
EFI83635.1 | celA | HMPREF0556_12320 | HMPREF0556_12323 | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | comEA protein; COG: COG1555; Pfam: PF00633; InterPro: IPR004509. | 0.478 |
EFI83635.1 | nadD | HMPREF0556_12320 | HMPREF0556_12319 | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.993 |
EFI83635.1 | rsfS | HMPREF0556_12320 | HMPREF0556_12321 | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.921 |
EFI83635.1 | tmcAL | HMPREF0556_12320 | HMPREF0556_10998 | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. | 0.503 |
EFI83635.1 | yhbY | HMPREF0556_12320 | HMPREF0556_12318 | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | RNA-binding protein, YhbY family; COG: COG1534; Pfam: PF01985; InterPro: IPR001890. | 0.864 |
EFI83635.1 | yqeG | HMPREF0556_12320 | HMPREF0556_12315 | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | HAD phosphatase, family IIIA; COG: COG2179; Pfam: PF00702; InterPro: IPR010021. | 0.848 |
EFI83635.1 | yqeH | HMPREF0556_12320 | HMPREF0556_12316 | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | Ribosome biogenesis GTPase YqeH; COG: COG1161; Pfam: PF01926; InterPro: IPR002917. | 0.848 |
UbiG | EFI83635.1 | HMPREF0556_12322 | HMPREF0556_12320 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | 0.657 |
UbiG | aroE | HMPREF0556_12322 | HMPREF0556_12317 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.602 |
UbiG | cap5F | HMPREF0556_12322 | HMPREF0556_12050 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | NAD dependent epimerase/dehydratase family protein; COG: COG0451; Pfam: PF01073; InterPro: IPR016040. | 0.503 |
UbiG | celA | HMPREF0556_12322 | HMPREF0556_12323 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | comEA protein; COG: COG1555; Pfam: PF00633; InterPro: IPR004509. | 0.558 |
UbiG | nadD | HMPREF0556_12322 | HMPREF0556_12319 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.641 |
UbiG | rsfS | HMPREF0556_12322 | HMPREF0556_12321 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.659 |
UbiG | tmcAL | HMPREF0556_12322 | HMPREF0556_10998 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. | 0.525 |
UbiG | yhbY | HMPREF0556_12322 | HMPREF0556_12318 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | RNA-binding protein, YhbY family; COG: COG1534; Pfam: PF01985; InterPro: IPR001890. | 0.733 |
UbiG | yqeG | HMPREF0556_12322 | HMPREF0556_12315 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | HAD phosphatase, family IIIA; COG: COG2179; Pfam: PF00702; InterPro: IPR010021. | 0.578 |
UbiG | yqeH | HMPREF0556_12322 | HMPREF0556_12316 | Methyltransferase domain protein; COG: COG0500; Pfam: PF08242; InterPro: IPR013217. | Ribosome biogenesis GTPase YqeH; COG: COG1161; Pfam: PF01926; InterPro: IPR002917. | 0.585 |
aroE | EFI83635.1 | HMPREF0556_12317 | HMPREF0556_12320 | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Hydrolase, HD family; COG: COG1713; Pfam: PF01966; InterPro: IPR005249. | 0.873 |