node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFK57847.1 | asnS | HMPREF0766_12920 | HMPREF0766_10196 | Exonuclease SbcCD, C subunit; COG: COG0419. | asparagine--tRNA ligase; COG: COG0017; Pfam: PF01336,PF00152; InterPro: IPR004522. | 0.856 |
EFK57847.1 | yciO | HMPREF0766_12920 | HMPREF0766_10197 | Exonuclease SbcCD, C subunit; COG: COG0419. | Sua5/YciO/YrdC/YwlC family protein; COG: COG0009; Pfam: PF01300; InterPro: IPR004388; Belongs to the SUA5 family. | 0.418 |
EFK58535.1 | yciO | HMPREF0766_11932 | HMPREF0766_10197 | Hypothetical protein. | Sua5/YciO/YrdC/YwlC family protein; COG: COG0009; Pfam: PF01300; InterPro: IPR004388; Belongs to the SUA5 family. | 0.442 |
asnS | EFK57847.1 | HMPREF0766_10196 | HMPREF0766_12920 | asparagine--tRNA ligase; COG: COG0017; Pfam: PF01336,PF00152; InterPro: IPR004522. | Exonuclease SbcCD, C subunit; COG: COG0419. | 0.856 |
asnS | yciO | HMPREF0766_10196 | HMPREF0766_10197 | asparagine--tRNA ligase; COG: COG0017; Pfam: PF01336,PF00152; InterPro: IPR004522. | Sua5/YciO/YrdC/YwlC family protein; COG: COG0009; Pfam: PF01300; InterPro: IPR004388; Belongs to the SUA5 family. | 0.536 |
gcp | ksgA | HMPREF0766_10121 | HMPREF0766_11120 | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.617 |
gcp | lolD | HMPREF0766_10121 | HMPREF0766_10194 | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | ABC transporter, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. | 0.620 |
gcp | yciO | HMPREF0766_10121 | HMPREF0766_10197 | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Sua5/YciO/YrdC/YwlC family protein; COG: COG0009; Pfam: PF01300; InterPro: IPR004388; Belongs to the SUA5 family. | 0.418 |
gcp | yeaZ | HMPREF0766_10121 | HMPREF0766_14436 | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Universal bacterial protein YeaZ; COG: COG1214; Pfam: PF00814; InterPro: IPR000905. | 0.998 |
ksgA | gcp | HMPREF0766_11120 | HMPREF0766_10121 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.617 |
ksgA | lolD | HMPREF0766_11120 | HMPREF0766_10194 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | ABC transporter, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. | 0.472 |
ksgA | truA | HMPREF0766_11120 | HMPREF0766_10790 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.565 |
ksgA | yciO | HMPREF0766_11120 | HMPREF0766_10197 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Sua5/YciO/YrdC/YwlC family protein; COG: COG0009; Pfam: PF01300; InterPro: IPR004388; Belongs to the SUA5 family. | 0.430 |
lolD | gcp | HMPREF0766_10194 | HMPREF0766_10121 | ABC transporter, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.620 |
lolD | ksgA | HMPREF0766_10194 | HMPREF0766_11120 | ABC transporter, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.472 |
lolD | yciO | HMPREF0766_10194 | HMPREF0766_10197 | ABC transporter, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. | Sua5/YciO/YrdC/YwlC family protein; COG: COG0009; Pfam: PF01300; InterPro: IPR004388; Belongs to the SUA5 family. | 0.421 |
nhaA | yciO | HMPREF0766_13276 | HMPREF0766_10197 | Na+/H+ antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. | Sua5/YciO/YrdC/YwlC family protein; COG: COG0009; Pfam: PF01300; InterPro: IPR004388; Belongs to the SUA5 family. | 0.480 |
prmC | yciO | HMPREF0766_10010 | HMPREF0766_10197 | protein-(glutamine-N5) methyltransferase, release factor-specific; COG: COG2890; Pfam: PF08241; InterPro: IPR004556. | Sua5/YciO/YrdC/YwlC family protein; COG: COG0009; Pfam: PF01300; InterPro: IPR004388; Belongs to the SUA5 family. | 0.818 |
truA | ksgA | HMPREF0766_10790 | HMPREF0766_11120 | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.565 |
truA | yciO | HMPREF0766_10790 | HMPREF0766_10197 | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | Sua5/YciO/YrdC/YwlC family protein; COG: COG0009; Pfam: PF01300; InterPro: IPR004388; Belongs to the SUA5 family. | 0.415 |