node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFK58373.1 | EFK59295.1 | HMPREF0766_11769 | HMPREF0766_10212 | Hypothetical protein. | Putative membrane protein; Pfam: PF00892; InterPro: IPR000620. | 0.467 |
EFK59295.1 | EFK58373.1 | HMPREF0766_10212 | HMPREF0766_11769 | Putative membrane protein; Pfam: PF00892; InterPro: IPR000620. | Hypothetical protein. | 0.467 |
EFK59295.1 | EFK59296.1 | HMPREF0766_10212 | HMPREF0766_10213 | Putative membrane protein; Pfam: PF00892; InterPro: IPR000620. | Permease, YjgP/YjgQ family; Pfam: PF03739; InterPro: IPR005495. | 0.781 |
EFK59295.1 | EFK59298.1 | HMPREF0766_10212 | HMPREF0766_10215 | Putative membrane protein; Pfam: PF00892; InterPro: IPR000620. | Glycosyltransferase, group 2 family protein; Pfam: PF00535; InterPro: IPR001173. | 0.422 |
EFK59295.1 | tgt | HMPREF0766_10212 | HMPREF0766_10214 | Putative membrane protein; Pfam: PF00892; InterPro: IPR000620. | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] | 0.725 |
EFK59296.1 | EFK59295.1 | HMPREF0766_10213 | HMPREF0766_10212 | Permease, YjgP/YjgQ family; Pfam: PF03739; InterPro: IPR005495. | Putative membrane protein; Pfam: PF00892; InterPro: IPR000620. | 0.781 |
EFK59296.1 | EFK59298.1 | HMPREF0766_10213 | HMPREF0766_10215 | Permease, YjgP/YjgQ family; Pfam: PF03739; InterPro: IPR005495. | Glycosyltransferase, group 2 family protein; Pfam: PF00535; InterPro: IPR001173. | 0.471 |
EFK59296.1 | tgt | HMPREF0766_10213 | HMPREF0766_10214 | Permease, YjgP/YjgQ family; Pfam: PF03739; InterPro: IPR005495. | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] | 0.828 |
EFK59298.1 | EFK59295.1 | HMPREF0766_10215 | HMPREF0766_10212 | Glycosyltransferase, group 2 family protein; Pfam: PF00535; InterPro: IPR001173. | Putative membrane protein; Pfam: PF00892; InterPro: IPR000620. | 0.422 |
EFK59298.1 | EFK59296.1 | HMPREF0766_10215 | HMPREF0766_10213 | Glycosyltransferase, group 2 family protein; Pfam: PF00535; InterPro: IPR001173. | Permease, YjgP/YjgQ family; Pfam: PF03739; InterPro: IPR005495. | 0.471 |
EFK59298.1 | tgt | HMPREF0766_10215 | HMPREF0766_10214 | Glycosyltransferase, group 2 family protein; Pfam: PF00535; InterPro: IPR001173. | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] | 0.538 |
tgt | EFK59295.1 | HMPREF0766_10214 | HMPREF0766_10212 | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] | Putative membrane protein; Pfam: PF00892; InterPro: IPR000620. | 0.725 |
tgt | EFK59296.1 | HMPREF0766_10214 | HMPREF0766_10213 | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] | Permease, YjgP/YjgQ family; Pfam: PF03739; InterPro: IPR005495. | 0.828 |
tgt | EFK59298.1 | HMPREF0766_10214 | HMPREF0766_10215 | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] | Glycosyltransferase, group 2 family protein; Pfam: PF00535; InterPro: IPR001173. | 0.538 |