STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFK60027.1Dinuclear metal center protein, YbgI family; COG: COG3323; Pfam: PF01784; InterPro: IPR002678; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. (365 aa)    
Predicted Functional Partners:
ribB
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.940
EFK60028.1
Putative zinc ribbon domain protein; Pfam: PF02591; InterPro: IPR003743.
 
  
 0.935
hisC
Histidinol-phosphate transaminase; COG: COG0079; Pfam: PF00155; InterPro: IPR005861; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
 0.860
folE
GTP cyclohydrolase I; COG: COG0302; Pfam: PF01227; InterPro: IPR001474.
    
 0.766
pyk
Pyruvate kinase; COG: COG0469; Pfam: PF00224,PF02887; InterPro: IPR001697; Belongs to the pyruvate kinase family.
   
 0.699
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; COG: COG0801; Pfam: PF01288; InterPro: IPR000550.
    
  0.693
queD
6-pyruvoyl tetrahydropterin synthase/QueD family protein; Pfam: PF01242; InterPro: IPR007115.
    
 0.672
rnhA
Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase H family.
  
  
 0.666
EFK60026.1
Hypothetical protein.
       0.664
relA
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
  0.637
Your Current Organism:
Sphingobacterium spiritivorum
NCBI taxonomy Id: 525373
Other names: S. spiritivorum ATCC 33861, Sphingobacterium spiritivorum ATCC 33861, Sphingobacterium spiritivorum str. ATCC 33861, Sphingobacterium spiritivorum strain ATCC 33861
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.