| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFK58978.1 | aroC | HMPREF0766_11094 | HMPREF0766_12835 | Hypothetical protein; COG: COG4121; Pfam: PF05430; InterPro: IPR008471. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.473 |
| EFK58978.1 | gltT2 | HMPREF0766_11094 | HMPREF0766_11095 | Hypothetical protein; COG: COG4121; Pfam: PF05430; InterPro: IPR008471. | Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; Pfam: PF00375; InterPro: IPR001991; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | 0.558 |
| EFK58978.1 | hisC | HMPREF0766_11094 | HMPREF0766_10326 | Hypothetical protein; COG: COG4121; Pfam: PF05430; InterPro: IPR008471. | Histidinol-phosphate transaminase; COG: COG0079; Pfam: PF00155; InterPro: IPR005861; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.418 |
| EFK58978.1 | pchB | HMPREF0766_11094 | HMPREF0766_10492 | Hypothetical protein; COG: COG4121; Pfam: PF05430; InterPro: IPR008471. | Salicylate biosynthesis protein PchB; Pfam: PF01817; InterPro: IPR002701. | 0.477 |
| EFK58978.1 | pheB | HMPREF0766_11094 | HMPREF0766_12837 | Hypothetical protein; COG: COG4121; Pfam: PF05430; InterPro: IPR008471. | Putative 3-deoxy-7-phosphoheptulonate synthase; COG: COG2876; Pfam: PF00793,PF01817; InterPro: IPR006268. | 0.444 |
| aroC | EFK58978.1 | HMPREF0766_12835 | HMPREF0766_11094 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Hypothetical protein; COG: COG4121; Pfam: PF05430; InterPro: IPR008471. | 0.473 |
| aroC | hisC | HMPREF0766_12835 | HMPREF0766_10326 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Histidinol-phosphate transaminase; COG: COG0079; Pfam: PF00155; InterPro: IPR005861; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.833 |
| aroC | pchB | HMPREF0766_12835 | HMPREF0766_10492 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Salicylate biosynthesis protein PchB; Pfam: PF01817; InterPro: IPR002701. | 0.818 |
| aroC | pheB | HMPREF0766_12835 | HMPREF0766_12837 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Putative 3-deoxy-7-phosphoheptulonate synthase; COG: COG2876; Pfam: PF00793,PF01817; InterPro: IPR006268. | 0.999 |
| gltT2 | EFK58978.1 | HMPREF0766_11095 | HMPREF0766_11094 | Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; Pfam: PF00375; InterPro: IPR001991; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | Hypothetical protein; COG: COG4121; Pfam: PF05430; InterPro: IPR008471. | 0.558 |
| hisC | EFK58978.1 | HMPREF0766_10326 | HMPREF0766_11094 | Histidinol-phosphate transaminase; COG: COG0079; Pfam: PF00155; InterPro: IPR005861; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Hypothetical protein; COG: COG4121; Pfam: PF05430; InterPro: IPR008471. | 0.418 |
| hisC | aroC | HMPREF0766_10326 | HMPREF0766_12835 | Histidinol-phosphate transaminase; COG: COG0079; Pfam: PF00155; InterPro: IPR005861; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.833 |
| hisC | pchB | HMPREF0766_10326 | HMPREF0766_10492 | Histidinol-phosphate transaminase; COG: COG0079; Pfam: PF00155; InterPro: IPR005861; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Salicylate biosynthesis protein PchB; Pfam: PF01817; InterPro: IPR002701. | 0.556 |
| hisC | pheB | HMPREF0766_10326 | HMPREF0766_12837 | Histidinol-phosphate transaminase; COG: COG0079; Pfam: PF00155; InterPro: IPR005861; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Putative 3-deoxy-7-phosphoheptulonate synthase; COG: COG2876; Pfam: PF00793,PF01817; InterPro: IPR006268. | 0.795 |
| pchB | EFK58978.1 | HMPREF0766_10492 | HMPREF0766_11094 | Salicylate biosynthesis protein PchB; Pfam: PF01817; InterPro: IPR002701. | Hypothetical protein; COG: COG4121; Pfam: PF05430; InterPro: IPR008471. | 0.477 |
| pchB | aroC | HMPREF0766_10492 | HMPREF0766_12835 | Salicylate biosynthesis protein PchB; Pfam: PF01817; InterPro: IPR002701. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.818 |
| pchB | hisC | HMPREF0766_10492 | HMPREF0766_10326 | Salicylate biosynthesis protein PchB; Pfam: PF01817; InterPro: IPR002701. | Histidinol-phosphate transaminase; COG: COG0079; Pfam: PF00155; InterPro: IPR005861; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.556 |
| pchB | pheB | HMPREF0766_10492 | HMPREF0766_12837 | Salicylate biosynthesis protein PchB; Pfam: PF01817; InterPro: IPR002701. | Putative 3-deoxy-7-phosphoheptulonate synthase; COG: COG2876; Pfam: PF00793,PF01817; InterPro: IPR006268. | 0.650 |
| pheB | EFK58978.1 | HMPREF0766_12837 | HMPREF0766_11094 | Putative 3-deoxy-7-phosphoheptulonate synthase; COG: COG2876; Pfam: PF00793,PF01817; InterPro: IPR006268. | Hypothetical protein; COG: COG4121; Pfam: PF05430; InterPro: IPR008471. | 0.444 |
| pheB | aroC | HMPREF0766_12837 | HMPREF0766_12835 | Putative 3-deoxy-7-phosphoheptulonate synthase; COG: COG2876; Pfam: PF00793,PF01817; InterPro: IPR006268. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.999 |