STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proBGlutamate 5-kinase; COG: COG0263; Pfam: PF00696,PF01472; InterPro: IPR005715. (344 aa)    
Predicted Functional Partners:
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 0.999
pruA
1-pyrroline-5-carboxylate dehydrogenase; COG: COG1012; Pfam: PF00171; InterPro: IPR005931; Belongs to the aldehyde dehydrogenase family.
     
 0.937
rocD
Ornithine aminotransferase; COG: COG4992; Pfam: PF00202; InterPro: IPR010164; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 0.838
EFK59114.1
Hypothetical protein.
       0.751
gltB
Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785.
 
  
 0.695
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.641
pdh
Proline dehydrogenase; Pfam: PF01619; InterPro: IPR002872.
    
 0.596
argD2
Aminotransferase, class III; COG: COG4992; Pfam: PF00202; InterPro: IPR005814; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 0.531
argD
Aminotransferase, class III; COG: COG4992; Pfam: PF00202; InterPro: IPR005814; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 0.511
ribB
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.504
Your Current Organism:
Sphingobacterium spiritivorum
NCBI taxonomy Id: 525373
Other names: S. spiritivorum ATCC 33861, Sphingobacterium spiritivorum ATCC 33861, Sphingobacterium spiritivorum str. ATCC 33861, Sphingobacterium spiritivorum strain ATCC 33861
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.