STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshBGlutathione synthetase, ATP-binding domain protein; COG: COG0189; Pfam: PF02955; InterPro: IPR004218; Belongs to the prokaryotic GSH synthase family. (335 aa)    
Predicted Functional Partners:
ggt
Gamma-glutamyltransferase; COG: COG0405; Pfam: PF01019; InterPro: IPR000101.
     
 0.942
EFK58634.1
Hypothetical protein; COG: COG3930; Pfam: PF08014; InterPro: IPR012548.
 
     0.938
gpo
Glutathione peroxidase; COG: COG0386; Pfam: PF00255; InterPro: IPR000889; Belongs to the glutathione peroxidase family.
     
 0.937
EFK58633.1
Hypothetical protein.
 
   
 0.931
gpo2
Glutathione peroxidase; COG: COG0386; Pfam: PF00255; InterPro: IPR012335; Belongs to the glutathione peroxidase family.
     
 0.911
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.865
pepD
Xaa-His dipeptidase; COG: COG2195; Pfam: PF01546,PF07687; InterPro: IPR001160.
     
 0.794
EFK58636.1
Hypothetical protein.
       0.757
pepA
Cytosol aminopeptidase family, catalytic domain protein; COG: COG0260; Pfam: PF00883; InterPro: IPR011356; Belongs to the peptidase M17 family.
   
 
 0.636
gltB
Class II glutamine amidotransferase; COG: COG0069; Pfam: PF00310,PF04898,PF01645,PF01493; InterPro: IPR013785.
    
 0.627
Your Current Organism:
Sphingobacterium spiritivorum
NCBI taxonomy Id: 525373
Other names: S. spiritivorum ATCC 33861, Sphingobacterium spiritivorum ATCC 33861, Sphingobacterium spiritivorum str. ATCC 33861, Sphingobacterium spiritivorum strain ATCC 33861
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.