Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFK58651.1Hypothetical protein; Pfam: PF04224; InterPro: IPR007339. (141 aa)    
Predicted Functional Partners:
EFK58649.1
Putative RNA polymerase sigma-70 factor, TIGR02943 family; COG: COG1595; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. ECF subfamily.
 
     0.742
msrA-2
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
       0.707
EFK58650.1
Hypothetical protein.
       0.567
EFK60084.1
Hypothetical protein.
  
     0.562
EFK57269.1
Glyoxalase family protein; Pfam: PF00903.
  
     0.528
EFK58972.1
Hypothetical protein.
  
     0.451
EFK55850.1
Hypothetical protein.
  
     0.451
EFK58609.1
Hypothetical protein.
  
     0.419
EFK57816.1
Hypothetical protein.
  
     0.407
Your Current Organism:
Sphingobacterium spiritivorum
NCBI taxonomy Id: 525373
Other names: S. spiritivorum ATCC 33861, Sphingobacterium spiritivorum ATCC 33861, Sphingobacterium spiritivorum str. ATCC 33861, Sphingobacterium spiritivorum strain ATCC 33861
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