STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
idiIsopentenyl-diphosphate delta-isomerase; COG: COG1443; Pfam: PF00293; InterPro: IPR011876. (177 aa)    
Predicted Functional Partners:
gds
Polyprenyl synthetase; COG: COG0142; Pfam: PF00348; InterPro: IPR008949; Belongs to the FPP/GGPP synthase family.
 
 
 0.966
crtB
Phytoene/squalene synthetase; COG: COG1562; Pfam: PF00494; InterPro: IPR002060.
 
 
 0.950
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
     
 0.948
crtZ
Fatty acid hydroxylase superfamily; Pfam: PF03897; InterPro: IPR005596.
 
  
 0.922
crtI
Phytoene desaturase; COG: COG1233; Pfam: PF01593; InterPro: IPR014105.
 
  
 0.836
EFK58810.1
Lycopene cyclase family protein; Pfam: PF05834; InterPro: IPR008671.
  
  
 0.819
EFK59005.1
FAD dependent oxidoreductase; COG: COG0654; Pfam: PF01494.
   
  
 0.744
hepT
Polyprenyl synthetase; COG: COG0142; Pfam: PF00348; InterPro: IPR008949; Belongs to the FPP/GGPP synthase family.
 
 
 0.627
uppS
Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
  
 
 0.580
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
   
 
 0.569
Your Current Organism:
Sphingobacterium spiritivorum
NCBI taxonomy Id: 525373
Other names: S. spiritivorum ATCC 33861, Sphingobacterium spiritivorum ATCC 33861, Sphingobacterium spiritivorum str. ATCC 33861, Sphingobacterium spiritivorum strain ATCC 33861
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.