STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFK58826.13-octaprenyl-4-hydroxybenzoate carboxy-lyase; COG: COG0043; Pfam: PF01977; InterPro: IPR002830; Belongs to the UbiD family. (612 aa)    
Predicted Functional Partners:
ubiX
Polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
 
 
 0.995
EFK57994.1
Putative 4-hydroxybenzoate polyprenyltransferase; COG: COG0382; Pfam: PF01040; InterPro: IPR006371; Belongs to the UbiA prenyltransferase family.
 
  
 0.988
mqnA
Putative ACR, COG1427; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
   
 0.809
mqnD
Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
  
   
 0.792
mqnB
Futalosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).
  
   
 0.784
mqnE
Menaquinone biosynthesis protein, SCO4494 family; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.
 
   
 0.772
EFK56789.1
Putative menaquinone biosynthesis protein, SCO4550 family; COG: COG1060; Pfam: PF04055; InterPro: IPR005244.
 
   
 0.772
EFK58827.1
Hypothetical protein; InterPro: IPR016040.
 
     0.634
hsfA
Sigma-54 interaction domain protein; COG: COG2204; Pfam: PF00072,PF00158,PF02954; InterPro: IPR002078.
       0.623
EFK59005.1
FAD dependent oxidoreductase; COG: COG0654; Pfam: PF01494.
    
 0.558
Your Current Organism:
Sphingobacterium spiritivorum
NCBI taxonomy Id: 525373
Other names: S. spiritivorum ATCC 33861, Sphingobacterium spiritivorum ATCC 33861, Sphingobacterium spiritivorum str. ATCC 33861, Sphingobacterium spiritivorum strain ATCC 33861
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