STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdhC-2Succinate dehydrogenase cytochrome B subunit, b558 family; InterPro: IPR011138. (218 aa)    
Predicted Functional Partners:
sdhA-2
Succinate dehydrogenase or fumarate reductase, flavoprotein subunit; COG: COG1053; Pfam: PF00890,PF02910; InterPro: IPR011280.
 
 
 0.995
frdB2
Succinate dehydrogenase and fumarate reductase iron-sulfur protein; Pfam: PF00037; InterPro: IPR012675.
 
 
 0.993
sdhA
Succinate dehydrogenase or fumarate reductase, flavoprotein subunit; COG: COG1053; Pfam: PF00890,PF02910; InterPro: IPR011280.
 
 
 0.979
frdB
Succinate dehydrogenase/fumarate reductase iron-sulfur subunit; COG: COG0479; Pfam: PF00111,PF00037; InterPro: IPR012675.
 
 
 0.972
EFK58092.1
Transporter, DASS family; COG: COG0471; Pfam: PF00939; InterPro: IPR001898.
 
     0.863
sucC
succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
 0.822
sucD
succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.822
sdhC
Succinate dehydrogenase cytochrome B subunit, b558 family; InterPro: IPR011138.
  
  
 
0.812
EFK58093.1
Phosphate-selective porin O and P; Pfam: PF07396.
       0.792
fahA2
FAH family protein; COG: COG0179; Pfam: PF01557; InterPro: IPR011234.
    
  0.741
Your Current Organism:
Sphingobacterium spiritivorum
NCBI taxonomy Id: 525373
Other names: S. spiritivorum ATCC 33861, Sphingobacterium spiritivorum ATCC 33861, Sphingobacterium spiritivorum str. ATCC 33861, Sphingobacterium spiritivorum strain ATCC 33861
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