STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gabDSuccinate-semialdehyde dehydrogenase; COG: COG1012; Pfam: PF00171; InterPro: IPR015590; Belongs to the aldehyde dehydrogenase family. (476 aa)    
Predicted Functional Partners:
sdhA
Succinate dehydrogenase or fumarate reductase, flavoprotein subunit; COG: COG1053; Pfam: PF00890,PF02910; InterPro: IPR011280.
   
 0.952
frdB
Succinate dehydrogenase/fumarate reductase iron-sulfur subunit; COG: COG0479; Pfam: PF00111,PF00037; InterPro: IPR012675.
   
 
 0.942
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
  
 
 0.938
gltA
Citrate (Si)-synthase; COG: COG0372; Pfam: PF00285; InterPro: IPR002020; Belongs to the citrate synthase family.
  
 0.931
frdB2
Succinate dehydrogenase and fumarate reductase iron-sulfur protein; Pfam: PF00037; InterPro: IPR012675.
   
 
 0.928
sucA
Oxoglutarate dehydrogenase (succinyl-transferring), E1 component; COG: COG0567; Pfam: PF00676,PF02779; InterPro: IPR011603.
  
 
 0.927
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
    
 0.917
mdh
Putative malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 0.917
mqo
Malate dehydrogenase (quinone); COG: COG0579; Pfam: PF06039; InterPro: IPR006231.
   
 
 0.916
EFK57140.1
Succinate CoA transferase; COG: COG0427; Pfam: PF02550; InterPro: IPR003702.
  
 
 0.909
Your Current Organism:
Sphingobacterium spiritivorum
NCBI taxonomy Id: 525373
Other names: S. spiritivorum ATCC 33861, Sphingobacterium spiritivorum ATCC 33861, Sphingobacterium spiritivorum str. ATCC 33861, Sphingobacterium spiritivorum strain ATCC 33861
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