| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFK57466.1 | tktA | HMPREF0766_12539 | HMPREF0766_12541 | Sigma-70 region 2; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. ECF subfamily. | Transketolase, thiamine diphosphate binding domain protein; COG: COG3959; Pfam: PF00456; InterPro: IPR005474. | 0.674 |
| EFK57466.1 | tktC | HMPREF0766_12539 | HMPREF0766_12540 | Sigma-70 region 2; Pfam: PF04542,PF08281; InterPro: IPR014284; Belongs to the sigma-70 factor family. ECF subfamily. | Transketolase, pyridine binding domain protein; COG: COG3958; Pfam: PF02779,PF02780; InterPro: IPR005475. | 0.850 |
| fbaA | fsa | HMPREF0766_13941 | HMPREF0766_12815 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.968 |
| fbaA | pfkA | HMPREF0766_13941 | HMPREF0766_10739 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.980 |
| fbaA | pfkA-2 | HMPREF0766_13941 | HMPREF0766_11297 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.978 |
| fbaA | pgi | HMPREF0766_13941 | HMPREF0766_11864 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.991 |
| fbaA | prs | HMPREF0766_13941 | HMPREF0766_11055 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Ribose-phosphate diphosphokinase; COG: COG0462; Pfam: PF00156; InterPro: IPR005946. | 0.616 |
| fbaA | tktA | HMPREF0766_13941 | HMPREF0766_12541 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Transketolase, thiamine diphosphate binding domain protein; COG: COG3959; Pfam: PF00456; InterPro: IPR005474. | 0.942 |
| fbaA | tktC | HMPREF0766_13941 | HMPREF0766_12540 | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | Transketolase, pyridine binding domain protein; COG: COG3958; Pfam: PF02779,PF02780; InterPro: IPR005475. | 0.941 |
| fsa | fbaA | HMPREF0766_12815 | HMPREF0766_13941 | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.968 |
| fsa | pfkA | HMPREF0766_12815 | HMPREF0766_10739 | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.946 |
| fsa | pfkA-2 | HMPREF0766_12815 | HMPREF0766_11297 | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.946 |
| fsa | pgi | HMPREF0766_12815 | HMPREF0766_11864 | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.981 |
| fsa | prs | HMPREF0766_12815 | HMPREF0766_11055 | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | Ribose-phosphate diphosphokinase; COG: COG0462; Pfam: PF00156; InterPro: IPR005946. | 0.577 |
| fsa | rpe | HMPREF0766_12815 | HMPREF0766_13563 | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | Ribulose-phosphate 3-epimerase; COG: COG0036; Pfam: PF00834; InterPro: IPR013785; Belongs to the ribulose-phosphate 3-epimerase family. | 0.868 |
| fsa | rpiB | HMPREF0766_12815 | HMPREF0766_12283 | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | Ribose-5-phosphate isomerase B; COG: COG0698; Pfam: PF02502; InterPro: IPR003500. | 0.714 |
| fsa | tktA | HMPREF0766_12815 | HMPREF0766_12541 | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | Transketolase, thiamine diphosphate binding domain protein; COG: COG3959; Pfam: PF00456; InterPro: IPR005474. | 0.967 |
| fsa | tktC | HMPREF0766_12815 | HMPREF0766_12540 | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | Transketolase, pyridine binding domain protein; COG: COG3958; Pfam: PF02779,PF02780; InterPro: IPR005475. | 0.962 |
| pfkA | fbaA | HMPREF0766_10739 | HMPREF0766_13941 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. | 0.980 |
| pfkA | fsa | HMPREF0766_10739 | HMPREF0766_12815 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.946 |