STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureFUrease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (228 aa)    
Predicted Functional Partners:
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.999
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.999
ureC
Urease, alpha subunit; COG: COG0804; Pfam: PF00449,PF01979; InterPro: IPR005848.
 
 
 0.997
hypB
Hydrogenase accessory protein HypB; COG: COG0378; Pfam: PF02492; InterPro: IPR004392.
  
 
 0.997
ureA
Urease, gamma subunit; COG: COG0831; Pfam: PF00547; InterPro: IPR002026; Belongs to the urease gamma subunit family.
 
 
 0.994
ureE
Urease accessory protein UreE domain protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.991
ureE-2
Urease accessory protein UreE.
 
  
 0.989
ureB
Urease, beta subunit; COG: COG0832; Pfam: PF00699; InterPro: IPR002019; Belongs to the urease beta subunit family.
 
 
 0.988
hypA
Hydrogenase expression/synthesis hypA family; Pfam: PF01155; InterPro: IPR000688.
     
 0.804
EFK57626.1
Periplasmic binding protein; Pfam: PF01497.
 
     0.777
Your Current Organism:
Sphingobacterium spiritivorum
NCBI taxonomy Id: 525373
Other names: S. spiritivorum ATCC 33861, Sphingobacterium spiritivorum ATCC 33861, Sphingobacterium spiritivorum str. ATCC 33861, Sphingobacterium spiritivorum strain ATCC 33861
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