STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFK57798.1Hypothetical protein; COG: COG3663. (160 aa)    
Predicted Functional Partners:
mutY
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
   
 0.883
EFK59725.1
Endonuclease/exonuclease/phosphatase family protein; Pfam: PF03372.
  
 
 0.870
xth
Exodeoxyribonuclease III; COG: COG0708; Pfam: PF03372; InterPro: IPR004808.
  
 
 0.870
EFK57797.1
Hypothetical protein; COG: COG0150; Pfam: PF02769.
       0.684
ogt
6-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
  
 0.682
EFK57796.1
Hypothetical protein; Pfam: PF05618; InterPro: IPR008503.
       0.674
czcD
Cadmium, cobalt and zinc/H(+)-K(+) antiporter; COG: COG1230; Pfam: PF01545; InterPro: IPR002524; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
  
    0.599
rimK
alpha-L-glutamate ligase, RimK family; COG: COG0189; Pfam: PF08443; InterPro: IPR004666; Belongs to the RimK family.
       0.449
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 
  0.449
EFK57803.1
Histidine kinase; COG: COG3275; Pfam: PF06580; InterPro: IPR010559.
 
     0.425
Your Current Organism:
Sphingobacterium spiritivorum
NCBI taxonomy Id: 525373
Other names: S. spiritivorum ATCC 33861, Sphingobacterium spiritivorum ATCC 33861, Sphingobacterium spiritivorum str. ATCC 33861, Sphingobacterium spiritivorum strain ATCC 33861
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.