STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFK55894.1Peptidase, S9A/B/C family, catalytic domain protein; COG: COG1506; Pfam: PF07676,PF00326; InterPro: IPR001375. (809 aa)    
Predicted Functional Partners:
cinA
Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994,PF02464; InterPro: IPR008135; Belongs to the CinA family.
  
 
  0.553
cinA2
Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family.
  
 
  0.553
ribB-2
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
       0.497
EFK55891.1
Cyclic nucleotide-binding domain protein; Pfam: PF00027; InterPro: IPR014710.
       0.495
EFK55893.1
Hypothetical protein.
       0.495
EFK57876.1
Peptidase, M28 family; Pfam: PF04389; InterPro: IPR007484.
  
    0.465
merR
DNA-binding helix-turn-helix protein; Pfam: PF01381; InterPro: IPR001387.
 
     0.450
EFK59208.1
Hypothetical protein; COG: COG1846; InterPro: IPR011991.
  
     0.432
EFK55890.1
Toxin-antitoxin system, toxin component, RelE family; Pfam: PF05973; InterPro: IPR009241.
 
     0.429
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
       0.414
Your Current Organism:
Sphingobacterium spiritivorum
NCBI taxonomy Id: 525373
Other names: S. spiritivorum ATCC 33861, Sphingobacterium spiritivorum ATCC 33861, Sphingobacterium spiritivorum str. ATCC 33861, Sphingobacterium spiritivorum strain ATCC 33861
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.