STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFK55951.1HAD hydrolase, family IA, variant 3; COG: COG0637; Pfam: PF00702; InterPro: IPR005834. (203 aa)    
Predicted Functional Partners:
otsB
Trehalose-phosphatase; COG: COG0380; Pfam: PF00982,PF02358; InterPro: IPR001830.
    
 0.724
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
 
 
  0.672
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
  0.613
hisB
Histidinol-phosphatase; COG: COG0131; Pfam: PF08645,PF00475; InterPro: IPR000807; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
    
 0.610
pdh
Proline dehydrogenase; Pfam: PF01619; InterPro: IPR002872.
  
  
 0.585
cinA
Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994,PF02464; InterPro: IPR008135; Belongs to the CinA family.
    
  0.562
cinA2
Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family.
    
  0.562
EFK58184.1
HAD hydrolase, family IA, variant 3; COG: COG0637; Pfam: PF00702; InterPro: IPR005834.
  
  
 
0.557
EFK58387.1
FAD linked oxidase, C-terminal domain protein; COG: COG0277; Pfam: PF01565,PF02913; InterPro: IPR004113.
    
  0.556
EFK56292.1
FAD binding domain protein; COG: COG0277; Pfam: PF01565,PF02913; InterPro: IPR004113.
    
  0.556
Your Current Organism:
Sphingobacterium spiritivorum
NCBI taxonomy Id: 525373
Other names: S. spiritivorum ATCC 33861, Sphingobacterium spiritivorum ATCC 33861, Sphingobacterium spiritivorum str. ATCC 33861, Sphingobacterium spiritivorum strain ATCC 33861
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.