node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFK55953.1 | EFK55955.1 | HMPREF0766_13156 | HMPREF0766_13158 | Hypothetical protein. | Hypothetical protein. | 0.664 |
EFK55953.1 | aroB | HMPREF0766_13156 | HMPREF0766_13157 | Hypothetical protein. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.777 |
EFK55955.1 | EFK55953.1 | HMPREF0766_13158 | HMPREF0766_13156 | Hypothetical protein. | Hypothetical protein. | 0.664 |
EFK55955.1 | aroB | HMPREF0766_13158 | HMPREF0766_13157 | Hypothetical protein. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.773 |
aroA2 | aroB | HMPREF0766_12836 | HMPREF0766_13157 | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.993 |
aroA2 | aroC | HMPREF0766_12836 | HMPREF0766_12835 | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.999 |
aroA2 | aroE | HMPREF0766_12836 | HMPREF0766_11925 | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Putative shikimate dehydrogenase; COG: COG0169; Pfam: PF08501,PF01488; InterPro: IPR016040. | 0.948 |
aroA2 | aroK | HMPREF0766_12836 | HMPREF0766_12218 | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.990 |
aroA2 | aroQ | HMPREF0766_12836 | HMPREF0766_12076 | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.642 |
aroA2 | pabA | HMPREF0766_12836 | HMPREF0766_10493 | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Glutamine amidotransferase, class I; COG: COG0512; Pfam: PF00117; InterPro: IPR006221. | 0.532 |
aroA2 | pheA | HMPREF0766_12836 | HMPREF0766_12838 | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Prephenate dehydratase; COG: COG0077; Pfam: PF00800; InterPro: IPR001086. | 0.921 |
aroA2 | pheB | HMPREF0766_12836 | HMPREF0766_12837 | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Putative 3-deoxy-7-phosphoheptulonate synthase; COG: COG2876; Pfam: PF00793,PF01817; InterPro: IPR006268. | 0.998 |
aroB | EFK55953.1 | HMPREF0766_13157 | HMPREF0766_13156 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | Hypothetical protein. | 0.777 |
aroB | EFK55955.1 | HMPREF0766_13157 | HMPREF0766_13158 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | Hypothetical protein. | 0.773 |
aroB | aroA2 | HMPREF0766_13157 | HMPREF0766_12836 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.993 |
aroB | aroC | HMPREF0766_13157 | HMPREF0766_12835 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.980 |
aroB | aroE | HMPREF0766_13157 | HMPREF0766_11925 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | Putative shikimate dehydrogenase; COG: COG0169; Pfam: PF08501,PF01488; InterPro: IPR016040. | 0.883 |
aroB | aroK | HMPREF0766_13157 | HMPREF0766_12218 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.988 |
aroB | aroQ | HMPREF0766_13157 | HMPREF0766_12076 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.994 |
aroB | pabA | HMPREF0766_13157 | HMPREF0766_10493 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | Glutamine amidotransferase, class I; COG: COG0512; Pfam: PF00117; InterPro: IPR006221. | 0.753 |