STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gloA2Glyoxalase family protein; COG: COG0346; Pfam: PF00903; InterPro: IPR004360. (129 aa)    
Predicted Functional Partners:
EFK59315.1
Metallo-beta-lactamase domain protein; COG: COG0491; Pfam: PF00753,PF00581; InterPro: IPR001279.
   
 
 0.798
ycbL
Metallo-beta-lactamase domain protein; COG: COG0491; Pfam: PF00753; InterPro: IPR001279.
     
 0.792
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 0.702
sdaA
L-serine ammonia-lyase; COG: COG1760; Pfam: PF03315,PF03313; InterPro: IPR004644; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
  
  0.677
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
  0.670
EFK56041.1
Transcriptional regulator, DeoR family; COG: COG1349; Pfam: PF08220,PF00455; InterPro: IPR014036.
       0.664
EFK57650.1
Acetyltransferase, GNAT family; COG: COG0454; Pfam: PF00583; InterPro: IPR016181.
 
      0.621
EFK57950.1
Metallo-beta-lactamase domain protein; COG: COG0491; Pfam: PF00753,PF00581; InterPro: IPR001279.
   
 
 0.603
EFK56039.1
Transporter, major facilitator family protein; Pfam: PF07690; InterPro: IPR011701.
       0.593
EFK60158.1
Rhodanese-like protein; COG: COG0607; Pfam: PF00581; InterPro: IPR001763.
   
 
 0.466
Your Current Organism:
Sphingobacterium spiritivorum
NCBI taxonomy Id: 525373
Other names: S. spiritivorum ATCC 33861, Sphingobacterium spiritivorum ATCC 33861, Sphingobacterium spiritivorum str. ATCC 33861, Sphingobacterium spiritivorum strain ATCC 33861
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