STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFK56596.1HAD hydrolase, family IA, variant 3; COG: COG1011; Pfam: PF00702. (225 aa)    
Predicted Functional Partners:
galM
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
  
 
  0.944
mro
Putative galactose mutarotase; Converts alpha-aldose to the beta-anomer.
  
 
  0.943
pgcA
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; COG: COG1109; Pfam: PF02878,PF02879,PF02880; InterPro: IPR016055.
  
 
  0.936
EFK57761.1
Hypothetical protein.
   
 
  0.936
glgC
Putative glucose-1-phosphate adenylyltransferase; COG: COG0448; Pfam: PF00483,PF00132; InterPro: IPR005835.
   
 
  0.741
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.673
EFK59359.1
ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600.
  
 
  0.616
EFK59362.1
ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600.
  
 
  0.615
EFK59356.1
ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600.
  
 
  0.614
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.586
Your Current Organism:
Sphingobacterium spiritivorum
NCBI taxonomy Id: 525373
Other names: S. spiritivorum ATCC 33861, Sphingobacterium spiritivorum ATCC 33861, Sphingobacterium spiritivorum str. ATCC 33861, Sphingobacterium spiritivorum strain ATCC 33861
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.