STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFK56661.1Methyltransferase domain protein; Pfam: PF08241; InterPro: IPR013216. (206 aa)    
Predicted Functional Partners:
EFK58969.1
Glycosyltransferase, group 1 family protein; Pfam: PF00534.
  
 
 0.744
EFK59005.1
FAD dependent oxidoreductase; COG: COG0654; Pfam: PF01494.
   
 0.741
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
 0.635
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
  0.624
EFK56644.1
Hypothetical protein.
  
     0.616
EFK58005.1
ABC1 family protein; COG: COG0661; Pfam: PF03109; InterPro: IPR004147.
   
 
 0.604
EFK57994.1
Putative 4-hydroxybenzoate polyprenyltransferase; COG: COG0382; Pfam: PF01040; InterPro: IPR006371; Belongs to the UbiA prenyltransferase family.
  
 0.547
EFK57787.1
DinB family protein; Pfam: PF05163.
 
   
 0.523
EFK58855.1
Methyltransferase domain protein; COG: COG0500; Pfam: PF08241; InterPro: IPR013216.
  
 
 0.509
rfbC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
 
 0.508
Your Current Organism:
Sphingobacterium spiritivorum
NCBI taxonomy Id: 525373
Other names: S. spiritivorum ATCC 33861, Sphingobacterium spiritivorum ATCC 33861, Sphingobacterium spiritivorum str. ATCC 33861, Sphingobacterium spiritivorum strain ATCC 33861
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