STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFL22638.1Dual specificity phosphatase, catalytic domain. (346 aa)    
Predicted Functional Partners:
SFL25851.1
WD40-like Beta Propeller Repeat.
   
 0.953
SFL26768.1
Hypothetical protein.
    
 0.948
SFL22672.1
Response regulator receiver domain-containing protein.
 
   
 0.933
SFL22654.1
Pyruvate, water dikinase.
 
   
 0.880
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
    
  0.872
SFL22689.1
PAS domain S-box-containing protein.
 
     0.844
SFL22705.1
Phosphonate transport system substrate-binding protein.
 
   
 0.807
SFM24555.1
EF hand.
    
 0.771
SFL23516.1
Hypothetical protein.
  
     0.770
SFL99946.1
Ribosomal protein S12 methylthiotransferase accessory factor.
 
 0.770
Your Current Organism:
Desulfomicrobium norvegicum
NCBI taxonomy Id: 52561
Other names: D. norvegicum, Desulfovibrio desulfuricans (strain Norway 4), Desulfovibrio desulfuricans norway, NCIMB 8310, strain Norway 4
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