SFL41271.1 protein (Desulfomicrobium norvegicum)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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[Homology]

Score

SFL41271.1

PilZ domain-containing protein. (156 aa)

Predicted Functional Partners:

SFL41234.1

0.727

SFL41254.1

0.727

SFL41217.1

0.606

pgi

0.582

SFL41291.1

0.493

SFL41177.1

0.492

SFL41156.1

0.483

SFL41138.1

0.474

pheT

0.450

pheS

0.425

Your Current Organism:

Desulfomicrobium norvegicum

NCBI taxonomy Id: 52561
Other names: D. norvegicum, Desulfovibrio desulfuricans (strain Norway 4), Desulfovibrio desulfuricans norway, NCIMB 8310, strain Norway 4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFL41138.1	SFL41156.1	SAMN05421830_10223	SAMN05421830_10224	DEAD/DEAH box helicase domain-containing protein.	Two-component system, NtrC family, response regulator.	0.763
SFL41138.1	SFL41177.1	SAMN05421830_10223	SAMN05421830_10225	DEAD/DEAH box helicase domain-containing protein.	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	0.760
SFL41138.1	SFL41217.1	SAMN05421830_10223	SAMN05421830_10227	DEAD/DEAH box helicase domain-containing protein.	Aspartate aminotransferase.	0.595
SFL41138.1	SFL41234.1	SAMN05421830_10223	SAMN05421830_10228	DEAD/DEAH box helicase domain-containing protein.	HD-like signal output (HDOD) domain, no enzymatic activity.	0.500
SFL41138.1	SFL41254.1	SAMN05421830_10223	SAMN05421830_10229	DEAD/DEAH box helicase domain-containing protein.	Type IV pilus assembly protein PilB.	0.500
SFL41138.1	SFL41271.1	SAMN05421830_10223	SAMN05421830_10230	DEAD/DEAH box helicase domain-containing protein.	PilZ domain-containing protein.	0.474
SFL41138.1	pgi	SAMN05421830_10223	SAMN05421830_10226	DEAD/DEAH box helicase domain-containing protein.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.619
SFL41156.1	SFL41138.1	SAMN05421830_10224	SAMN05421830_10223	Two-component system, NtrC family, response regulator.	DEAD/DEAH box helicase domain-containing protein.	0.763
SFL41156.1	SFL41177.1	SAMN05421830_10224	SAMN05421830_10225	Two-component system, NtrC family, response regulator.	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	0.922
SFL41156.1	SFL41217.1	SAMN05421830_10224	SAMN05421830_10227	Two-component system, NtrC family, response regulator.	Aspartate aminotransferase.	0.607
SFL41156.1	SFL41234.1	SAMN05421830_10224	SAMN05421830_10228	Two-component system, NtrC family, response regulator.	HD-like signal output (HDOD) domain, no enzymatic activity.	0.550
SFL41156.1	SFL41254.1	SAMN05421830_10224	SAMN05421830_10229	Two-component system, NtrC family, response regulator.	Type IV pilus assembly protein PilB.	0.512
SFL41156.1	SFL41271.1	SAMN05421830_10224	SAMN05421830_10230	Two-component system, NtrC family, response regulator.	PilZ domain-containing protein.	0.483
SFL41156.1	pgi	SAMN05421830_10224	SAMN05421830_10226	Two-component system, NtrC family, response regulator.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.697
SFL41177.1	SFL41138.1	SAMN05421830_10225	SAMN05421830_10223	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	DEAD/DEAH box helicase domain-containing protein.	0.760
SFL41177.1	SFL41156.1	SAMN05421830_10225	SAMN05421830_10224	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	Two-component system, NtrC family, response regulator.	0.922
SFL41177.1	SFL41217.1	SAMN05421830_10225	SAMN05421830_10227	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	Aspartate aminotransferase.	0.620
SFL41177.1	SFL41234.1	SAMN05421830_10225	SAMN05421830_10228	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	HD-like signal output (HDOD) domain, no enzymatic activity.	0.555
SFL41177.1	SFL41254.1	SAMN05421830_10225	SAMN05421830_10229	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	Type IV pilus assembly protein PilB.	0.543
SFL41177.1	SFL41271.1	SAMN05421830_10225	SAMN05421830_10230	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.	PilZ domain-containing protein.	0.492

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Network Stats

number of nodes:

3

number of edges:

2

average node degree:

1.33

avg. local clustering coefficient:

0.667

expected number of edges:

2

PPI enrichment p-value:

0.527

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 110

1.61

3.73

4.05e-15

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

11 of 53

1.93

5.9

1.36e-18

GO:0019843

rRNA binding

5 of 42

1.69

2.08

1.05e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 56

1.91

5.87

3.96e-19

GO:0044391

Ribosomal subunit

3 of 14

1.94

1.91

0.00012

GO:0015934

Large ribosomal subunit

2 of 8

2.01

1.28

0.0033

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:133

Structural constituent of ribosome

10 of 37

2.04

6.12

5.99e-17

CL:136

Structural constituent of ribosome

8 of 21

2.19

5.99

1.40e-14

CL:105

Translation, and Protein transport

11 of 111

1.61

3.78

1.21e-15

CL:187

Structural constituent of ribosome

2 of 10

1.91

0.9

0.0189

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

11 of 55

1.91

5.93

3.50e-19

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

9 of 40

1.96

5.17

1.50e-14

GOCC:0022626

Cytosolic ribosome

4 of 11

2.17

2.92

1.23e-06

GOCC:0043232

Intracellular non-membrane-bounded organelle

10 of 138

1.47

2.86

1.63e-12

GOCC:0044391

Ribosomal subunit

4 of 16

2.01

2.58

3.73e-06

GOCC:0022625

Cytosolic large ribosomal subunit

2 of 4

2.31

1.41

0.0023

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

11 of 61

1.87

5.55

1.55e-18

KW-0699

rRNA-binding

5 of 38

1.73

2.37

1.84e-06

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