node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFL28203.1 | SFL33836.1 | SAMN05421830_101335 | SAMN05421830_101673 | Hypothetical protein. | preQ(0) biosynthesis protein QueD. | 0.710 |
SFL28203.1 | SFL41291.1 | SAMN05421830_101335 | SAMN05421830_10231 | Hypothetical protein. | DNA-binding transcriptional regulator, MerR family. | 0.414 |
SFL28203.1 | SFL83633.1 | SAMN05421830_101335 | SAMN05421830_10790 | Hypothetical protein. | 6-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase. | 0.710 |
SFL28203.1 | queE | SAMN05421830_101335 | SAMN05421830_10791 | Hypothetical protein. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.835 |
SFL28203.1 | queF | SAMN05421830_101335 | SAMN05421830_10793 | Hypothetical protein. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.940 |
SFL33836.1 | SFL28203.1 | SAMN05421830_101673 | SAMN05421830_101335 | preQ(0) biosynthesis protein QueD. | Hypothetical protein. | 0.710 |
SFL33836.1 | SFL93405.1 | SAMN05421830_101673 | SAMN05421830_109112 | preQ(0) biosynthesis protein QueD. | 7-cyano-7-deazaguanine synthase (queuosine biosynthesis). | 0.710 |
SFL33836.1 | queC | SAMN05421830_101673 | SAMN05421830_10792 | preQ(0) biosynthesis protein QueD. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.918 |
SFL33836.1 | queE | SAMN05421830_101673 | SAMN05421830_10791 | preQ(0) biosynthesis protein QueD. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.979 |
SFL33836.1 | queF | SAMN05421830_101673 | SAMN05421830_10793 | preQ(0) biosynthesis protein QueD. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.939 |
SFL41291.1 | SFL28203.1 | SAMN05421830_10231 | SAMN05421830_101335 | DNA-binding transcriptional regulator, MerR family. | Hypothetical protein. | 0.414 |
SFL41291.1 | SFL93405.1 | SAMN05421830_10231 | SAMN05421830_109112 | DNA-binding transcriptional regulator, MerR family. | 7-cyano-7-deazaguanine synthase (queuosine biosynthesis). | 0.414 |
SFL41291.1 | queC | SAMN05421830_10231 | SAMN05421830_10792 | DNA-binding transcriptional regulator, MerR family. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.414 |
SFL41291.1 | queF | SAMN05421830_10231 | SAMN05421830_10793 | DNA-binding transcriptional regulator, MerR family. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.834 |
SFL41291.1 | tgt | SAMN05421830_10231 | SAMN05421830_101183 | DNA-binding transcriptional regulator, MerR family. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] | 0.624 |
SFL83633.1 | SFL28203.1 | SAMN05421830_10790 | SAMN05421830_101335 | 6-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase. | Hypothetical protein. | 0.710 |
SFL83633.1 | SFL93405.1 | SAMN05421830_10790 | SAMN05421830_109112 | 6-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase. | 7-cyano-7-deazaguanine synthase (queuosine biosynthesis). | 0.710 |
SFL83633.1 | queC | SAMN05421830_10790 | SAMN05421830_10792 | 6-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.972 |
SFL83633.1 | queE | SAMN05421830_10790 | SAMN05421830_10791 | 6-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.992 |
SFL83633.1 | queF | SAMN05421830_10790 | SAMN05421830_10793 | 6-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.983 |