SFL92015.1 protein (Desulfomicrobium norvegicum)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

SFL92015.1

Putative amidoligase enzyme. (320 aa)

Predicted Functional Partners:

SFL91971.1

0.949

SFL91948.1

0.948

SFL45387.1

0.881

SFL31987.1

0.874

SFL92186.1

0.853

SFL66038.1

0.850

SFL33239.1

0.828

SFL92330.1

0.828

SFL92467.1

0.824

SFL92406.1

0.823

Your Current Organism:

Desulfomicrobium norvegicum

NCBI taxonomy Id: 52561
Other names: D. norvegicum, Desulfovibrio desulfuricans (strain Norway 4), Desulfovibrio desulfuricans norway, NCIMB 8310, strain Norway 4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SFL31987.1	SFL66038.1	SAMN05421830_101571	SAMN05421830_104243	Molybdate/tungstate transport system permease protein.	Molybdate transport system ATP-binding protein.	0.997
SFL31987.1	SFL92015.1	SAMN05421830_101571	SAMN05421830_10954	Molybdate/tungstate transport system permease protein.	Putative amidoligase enzyme.	0.874
SFL33239.1	SFL45387.1	SAMN05421830_101640	SAMN05421830_102234	Uroporphyrinogen III methyltransferase / synthase.	Sulfate adenylyltransferase.	0.823
SFL33239.1	SFL66038.1	SAMN05421830_101640	SAMN05421830_104243	Uroporphyrinogen III methyltransferase / synthase.	Molybdate transport system ATP-binding protein.	0.588
SFL33239.1	SFL92015.1	SAMN05421830_101640	SAMN05421830_10954	Uroporphyrinogen III methyltransferase / synthase.	Putative amidoligase enzyme.	0.828
SFL45387.1	SFL33239.1	SAMN05421830_102234	SAMN05421830_101640	Sulfate adenylyltransferase.	Uroporphyrinogen III methyltransferase / synthase.	0.823
SFL45387.1	SFL66038.1	SAMN05421830_102234	SAMN05421830_104243	Sulfate adenylyltransferase.	Molybdate transport system ATP-binding protein.	0.484
SFL45387.1	SFL92015.1	SAMN05421830_102234	SAMN05421830_10954	Sulfate adenylyltransferase.	Putative amidoligase enzyme.	0.881
SFL66038.1	SFL31987.1	SAMN05421830_104243	SAMN05421830_101571	Molybdate transport system ATP-binding protein.	Molybdate/tungstate transport system permease protein.	0.997
SFL66038.1	SFL33239.1	SAMN05421830_104243	SAMN05421830_101640	Molybdate transport system ATP-binding protein.	Uroporphyrinogen III methyltransferase / synthase.	0.588
SFL66038.1	SFL45387.1	SAMN05421830_104243	SAMN05421830_102234	Molybdate transport system ATP-binding protein.	Sulfate adenylyltransferase.	0.484
SFL66038.1	SFL92015.1	SAMN05421830_104243	SAMN05421830_10954	Molybdate transport system ATP-binding protein.	Putative amidoligase enzyme.	0.850
SFL91948.1	SFL91971.1	SAMN05421830_10951	SAMN05421830_10952	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family.	Glutamine amidotransferase domain-containing protein.	0.984
SFL91948.1	SFL92015.1	SAMN05421830_10951	SAMN05421830_10954	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family.	Putative amidoligase enzyme.	0.948
SFL91948.1	SFL92186.1	SAMN05421830_10951	SAMN05421830_10961	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family.	Putative baseplate assembly protein.	0.849
SFL91948.1	SFL92330.1	SAMN05421830_10951	SAMN05421830_10968	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family.	Hypothetical protein.	0.825
SFL91948.1	SFL92406.1	SAMN05421830_10951	SAMN05421830_10971	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family.	Phage protein D.	0.826
SFL91948.1	SFL92467.1	SAMN05421830_10951	SAMN05421830_10974	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family.	Hypothetical protein.	0.629
SFL91971.1	SFL91948.1	SAMN05421830_10952	SAMN05421830_10951	Glutamine amidotransferase domain-containing protein.	Uncharacterized conserved protein YtfP, gamma-glutamylcyclotransferase (GGCT)/AIG2-like family.	0.984
SFL91971.1	SFL92015.1	SAMN05421830_10952	SAMN05421830_10954	Glutamine amidotransferase domain-containing protein.	Putative amidoligase enzyme.	0.949

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

17

average node degree:

3.09

avg. local clustering coefficient:

0.787

expected number of edges:

10

PPI enrichment p-value:

0.0391

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0055085

Transmembrane transport

10 of 249

0.85

0.84

1.28e-05

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042626

ATPase-coupled transmembrane transporter activity

5 of 57

1.19

1.12

0.00033

GO:0140359

ABC-type transporter activity

4 of 39

1.26

1.04

0.0016

GO:0005524

ATP binding

10 of 261

0.83

0.82

1.05e-05

GO:0022857

Transmembrane transporter activity

8 of 210

0.83

0.76

9.66e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016020

Membrane

10 of 571

0.49

0.38

0.0041

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2923

Transcription regulators MarR/SlyA-like, and ABC transporter transmembrane region

4 of 5

2.15

2.51

9.61e-06

CL:2919

Mixed, incl. ABC transporter transmembrane region, and ABC transporter, CbiO/EcfA subunit

5 of 31

1.46

1.59

5.78e-05

CL:2914

Mixed, incl. ABC transporters, and Latent infection - Other responses of Mtb to phagocytosis

9 of 108

1.17

1.51

1.53e-07

CL:2915

Mixed, incl. ABC transporters, and Latent infection - Other responses of Mtb to phagocytosis

8 of 93

1.18

1.45

1.18e-06

CL:2916

Mixed, incl. Latent infection - Other responses of Mtb to phagocytosis, and ABC transporters

7 of 82

1.18

1.34

9.66e-06

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

adc02010

ABC transporters

6 of 90

1.07

0.97

0.00042

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1222449

Mtb iron assimilation by chelation

2 of 15

1.37

0.62

0.0483

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005886

Plasma membrane

7 of 236

0.72

0.49

0.0111

GOCC:0016020

Membrane

8 of 319

0.65

0.45

0.0111

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-1278

Translocase

3 of 10

1.73

1.29

0.0020

KW-0067

ATP-binding

10 of 211

0.92

1.02

4.39e-07

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR017871

ABC transporter-like, conserved site

10 of 60

1.47

2.74

1.49e-11

IPR003439

ABC transporter-like, ATP-binding domain

10 of 67

1.42

2.57

2.05e-11

IPR003593

AAA+ ATPase domain

10 of 84

1.32

2.18

1.12e-10

IPR027417

P-loop containing nucleoside triphosphate hydrolase

10 of 157

1.05

1.32

3.16e-08

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00382

ATPases associated with a variety of cellular activities

10 of 81

1.34

2.29

2.19e-11

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