node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDK45011.1 | SDK46332.1 | SAMN04487971_10140 | SAMN04487971_10184 | Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. | Phosphoserine phosphatase. | 0.907 |
SDK45011.1 | SDK69602.1 | SAMN04487971_10140 | SAMN04487971_102296 | Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.893 |
SDK45011.1 | SDL61593.1 | SAMN04487971_10140 | SAMN04487971_1153 | Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. | Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. | 0.853 |
SDK45011.1 | glyA | SAMN04487971_10140 | SAMN04487971_10569 | Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.910 |
SDK45011.1 | ilvA | SAMN04487971_10140 | SAMN04487971_107196 | Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.906 |
SDK45011.1 | trpA | SAMN04487971_10140 | SAMN04487971_103271 | Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.892 |
SDK45011.1 | trpB | SAMN04487971_10140 | SAMN04487971_10954 | Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.891 |
SDK46332.1 | SDK45011.1 | SAMN04487971_10184 | SAMN04487971_10140 | Phosphoserine phosphatase. | Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. | 0.907 |
SDK46332.1 | SDK46364.1 | SAMN04487971_10184 | SAMN04487971_10186 | Phosphoserine phosphatase. | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.993 |
SDK46332.1 | SDK69602.1 | SAMN04487971_10184 | SAMN04487971_102296 | Phosphoserine phosphatase. | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.913 |
SDK46332.1 | SDL00735.1 | SAMN04487971_10184 | SAMN04487971_105105 | Phosphoserine phosphatase. | Serine O-acetyltransferase. | 0.957 |
SDK46332.1 | SDL61593.1 | SAMN04487971_10184 | SAMN04487971_1153 | Phosphoserine phosphatase. | Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase. | 0.907 |
SDK46332.1 | glyA | SAMN04487971_10184 | SAMN04487971_10569 | Phosphoserine phosphatase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.971 |
SDK46332.1 | hisF | SAMN04487971_10184 | SAMN04487971_10859 | Phosphoserine phosphatase. | Cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.890 |
SDK46332.1 | ilvA | SAMN04487971_10184 | SAMN04487971_107196 | Phosphoserine phosphatase. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.911 |
SDK46332.1 | trpA | SAMN04487971_10184 | SAMN04487971_103271 | Phosphoserine phosphatase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.892 |
SDK46332.1 | trpB | SAMN04487971_10184 | SAMN04487971_10954 | Phosphoserine phosphatase. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.915 |
SDK46364.1 | SDK46332.1 | SAMN04487971_10186 | SAMN04487971_10184 | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Phosphoserine phosphatase. | 0.993 |
SDK46364.1 | SDK69602.1 | SAMN04487971_10186 | SAMN04487971_102296 | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.631 |
SDK46364.1 | SDL00735.1 | SAMN04487971_10186 | SAMN04487971_105105 | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | Serine O-acetyltransferase. | 0.422 |