node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDK83416.1 | SDL10314.1 | SAMN04487971_103242 | SAMN04487971_106112 | Exonuclease RecJ. | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | 0.468 |
SDK83416.1 | SDL35408.1 | SAMN04487971_103242 | SAMN04487971_10988 | Exonuclease RecJ. | ATP-dependent DNA helicase RecG. | 0.629 |
SDK83416.1 | dnaA | SAMN04487971_103242 | SAMN04487971_102276 | Exonuclease RecJ. | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.458 |
SDK83416.1 | polA | SAMN04487971_103242 | SAMN04487971_105217 | Exonuclease RecJ. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.544 |
SDK83416.1 | recF | SAMN04487971_103242 | SAMN04487971_102278 | Exonuclease RecJ. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.448 |
SDK83416.1 | topA | SAMN04487971_103242 | SAMN04487971_101301 | Exonuclease RecJ. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.424 |
SDK94384.1 | SDL35408.1 | SAMN04487971_104176 | SAMN04487971_10988 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | ATP-dependent DNA helicase RecG. | 0.588 |
SDL10314.1 | SDK83416.1 | SAMN04487971_106112 | SAMN04487971_103242 | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | Exonuclease RecJ. | 0.468 |
SDL10314.1 | SDL35408.1 | SAMN04487971_106112 | SAMN04487971_10988 | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | ATP-dependent DNA helicase RecG. | 0.652 |
SDL10314.1 | dnaA | SAMN04487971_106112 | SAMN04487971_102276 | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.436 |
SDL10314.1 | ligA | SAMN04487971_106112 | SAMN04487971_10987 | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.930 |
SDL10314.1 | polA | SAMN04487971_106112 | SAMN04487971_105217 | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.838 |
SDL10314.1 | recA | SAMN04487971_106112 | SAMN04487971_102255 | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | Recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.971 |
SDL10314.1 | recF | SAMN04487971_106112 | SAMN04487971_102278 | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.641 |
SDL10314.1 | ruvA | SAMN04487971_106112 | SAMN04487971_101274 | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.440 |
SDL10314.1 | topA | SAMN04487971_106112 | SAMN04487971_101301 | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.775 |
SDL35408.1 | SDK83416.1 | SAMN04487971_10988 | SAMN04487971_103242 | ATP-dependent DNA helicase RecG. | Exonuclease RecJ. | 0.629 |
SDL35408.1 | SDK94384.1 | SAMN04487971_10988 | SAMN04487971_104176 | ATP-dependent DNA helicase RecG. | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.588 |
SDL35408.1 | SDL10314.1 | SAMN04487971_10988 | SAMN04487971_106112 | ATP-dependent DNA helicase RecG. | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | 0.652 |
SDL35408.1 | dnaA | SAMN04487971_10988 | SAMN04487971_102276 | ATP-dependent DNA helicase RecG. | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.581 |