STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cprANADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (694 aa)    
Predicted Functional Partners:
EV44_g0475
Putative cytochrome p450 family protein.
 
  
 
 0.922
EV44_g5400
Putative cytochrome p450.
 
  
 
 0.922
EV44_g0589
Putative benzoate 4-monooxygenase; Belongs to the cytochrome P450 family.
 
  
 
 0.893
DRE2
Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...]
    
 0.891
EV44_g0345
Putative heme steroid binding protein; Belongs to the cytochrome b5 family.
    
 0.858
EV44_g1851
Putative of heme oxygenase superfamily.
    
 
 0.839
EV44_g6370
Putative homocysteine s-methyltransferase.
  
 0.827
EV44_g2233
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
    
 0.811
EV44_g2354
Putative membrane associated chaperone.
    
 0.790
EV44_g5265
Putative flavin reductase family protein.
    
 0.766
Your Current Organism:
Erysiphe necator
NCBI taxonomy Id: 52586
Other names: E. necator, Uncinula necator, grape powdery mildew
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