STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EV44_g0838Putative signal transducer protein. (1295 aa)    
Predicted Functional Partners:
EV44_g0804
3'-5' exonuclease domain-containing protein.
   
 0.998
EV44_g1990
Putative dna damage response protein.
    
 0.964
EV44_g1875
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.962
EV44_g4583
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 0.948
EV44_g4467
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability.
    
 0.941
EV44_g5766
Putative dna repair protein rad50.
    
 0.923
EV44_g5215
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.923
EV44_g0561
Putative brct domain-containing protein.
   
 0.915
EV44_g1233
Putative dna damage repair protein.
    
 0.914
EV44_g2556
DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.
   
 0.907
Your Current Organism:
Erysiphe necator
NCBI taxonomy Id: 52586
Other names: E. necator, Uncinula necator, grape powdery mildew
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.