STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EV44_g2085Putative nucleosome binding protein. (107 aa)    
Predicted Functional Partners:
EV44_g5027
Histone H2A; Belongs to the histone H2A family.
   
 0.981
EV44_g0769
FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]
 
 
 0.935
EV44_g2327
Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family.
    
 0.889
EV44_g6256
Putative transcription factor tfiih subunit.
    
 0.878
EV44_g5814
Putative dna repair helicase rad25.
   
 0.877
EV44_g5332
Putative actin-related arp5 class; Belongs to the actin family.
    
 0.874
EV44_g6260
Putative transcription elongation complex subunit.
   
 0.837
EV44_g5694
General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.
    
 0.824
EV44_g1212
Putative iswi chromatin-remodeling complex atpase isw2.
    
 0.818
EV44_g2756
Putative dna repair helicase rad3.
    
 0.808
Your Current Organism:
Erysiphe necator
NCBI taxonomy Id: 52586
Other names: E. necator, Uncinula necator, grape powdery mildew
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.