STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EV44_g4369D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (462 aa)    
Predicted Functional Partners:
EV44_g6203
Putative phosphoserine aminotransferase.
 
 0.996
EV44_g2842
Tryptophan synthase.
  
 0.956
EV44_g4569
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 0.877
EV44_g1124
Putative phosphoserine phosphatase.
  
 0.858
EV44_g2673
Putative fmn-dependent dehydrogenase; Belongs to the cytochrome b5 family.
  
 
 0.857
EV44_g1494
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.856
EV44_g2837
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.856
EV44_g1428
Glyceraldehyde-3-phosphate dehydrogenase.
    
 0.856
EV44_g1709
Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.
    
 0.834
EV44_g1628
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.832
Your Current Organism:
Erysiphe necator
NCBI taxonomy Id: 52586
Other names: E. necator, Uncinula necator, grape powdery mildew
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.