| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EV44_g0195 | EV44_g0804 | A0A0B1PBY0 | A0A0B1NYH5 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 3'-5' exonuclease domain-containing protein. | 0.845 |
| EV44_g0195 | EV44_g1175 | A0A0B1PBY0 | A0A0B1NYX9 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Putative ubiquitin-like modifier. | 0.905 |
| EV44_g0195 | EV44_g1418 | A0A0B1PBY0 | A0A0B1PGK1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Putative qde3-like protein. | 0.840 |
| EV44_g0195 | EV44_g1890 | A0A0B1PBY0 | A0A0B1P6R7 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Putative tyrosyl-dna phosphodiesterase domain protein. | 0.864 |
| EV44_g0195 | EV44_g2258 | A0A0B1PBY0 | A0A0B1P1E0 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Putative swi snf complex protein. | 0.818 |
| EV44_g0195 | EV44_g5624 | A0A0B1PBY0 | A0A0B1NWQ2 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.987 |
| EV44_g0195 | EV44_g5702 | A0A0B1PBY0 | A0A0B1PAH1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.840 |
| EV44_g0195 | EV44_g6313 | A0A0B1PBY0 | A0A0B1PIU5 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Putative sumo conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | 0.899 |
| EV44_g0195 | EV44_g6371 | A0A0B1PBY0 | A0A0B1NUV4 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.890 |
| EV44_g0195 | EV44_g6381 | A0A0B1PBY0 | A0A0B1P582 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Putative tyrosyl-dna phosphodiesterase. | 0.969 |
| EV44_g0804 | EV44_g0195 | A0A0B1NYH5 | A0A0B1PBY0 | 3'-5' exonuclease domain-containing protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.845 |
| EV44_g0804 | EV44_g1175 | A0A0B1NYH5 | A0A0B1NYX9 | 3'-5' exonuclease domain-containing protein. | Putative ubiquitin-like modifier. | 0.919 |
| EV44_g0804 | EV44_g1418 | A0A0B1NYH5 | A0A0B1PGK1 | 3'-5' exonuclease domain-containing protein. | Putative qde3-like protein. | 0.691 |
| EV44_g0804 | EV44_g5624 | A0A0B1NYH5 | A0A0B1NWQ2 | 3'-5' exonuclease domain-containing protein. | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.786 |
| EV44_g0804 | EV44_g5702 | A0A0B1NYH5 | A0A0B1PAH1 | 3'-5' exonuclease domain-containing protein. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.691 |
| EV44_g0804 | EV44_g6313 | A0A0B1NYH5 | A0A0B1PIU5 | 3'-5' exonuclease domain-containing protein. | Putative sumo conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. | 0.881 |
| EV44_g0804 | EV44_g6371 | A0A0B1NYH5 | A0A0B1NUV4 | 3'-5' exonuclease domain-containing protein. | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.823 |
| EV44_g1175 | EV44_g0195 | A0A0B1NYX9 | A0A0B1PBY0 | Putative ubiquitin-like modifier. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.905 |
| EV44_g1175 | EV44_g0804 | A0A0B1NYX9 | A0A0B1NYH5 | Putative ubiquitin-like modifier. | 3'-5' exonuclease domain-containing protein. | 0.919 |
| EV44_g1175 | EV44_g1418 | A0A0B1NYX9 | A0A0B1PGK1 | Putative ubiquitin-like modifier. | Putative qde3-like protein. | 0.894 |
STRING v12.5 is now available!
