STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EV44_g4864Uncharacterized protein. (921 aa)    
Predicted Functional Partners:
EV44_g5241
Putative u3 small nucleolar rna-associated protein 18.
 
      0.899
EV44_g1728
Putative 5-amino-6-(5-phosphoribosylamino)uracil reductase.
  
 
 0.706
EV44_g2391
Putative adenosine kinase.
  
 
 0.706
EV44_g0722
Putative pfkb family carbohydrate kinase.
  
 
 0.706
EV44_g2780
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 
 0.706
EV44_g1680
Putative purine nucleoside phosphorylase.
  
 
  0.631
EV44_g1133
Putative inosine-uridine preferring nucleoside hydrolase.
  
 
  0.622
EV44_g2092
Putative dihydroorotate reductase.
   
 
  0.614
EV44_g1759
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
  0.573
EV44_g3450
Putative drap deaminase.
    
  0.522
Your Current Organism:
Erysiphe necator
NCBI taxonomy Id: 52586
Other names: E. necator, Uncinula necator, grape powdery mildew
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.