STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dbac_3209Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. (1001 aa)    
Predicted Functional Partners:
Dbac_3443
Glutamate dehydrogenase (NADP(+)); PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: dps:DP2840 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.963
Dbac_1640
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamine amidotransferase class-II; KEGG: gsu:GSU3450 glutamate synthase-related protein.
  
 
 0.961
Dbac_1371
PFAM: ferredoxin-dependent glutamate synthase; 4Fe- 4S ferredoxin iron-sulfur binding domain protein; KEGG: dvl:Dvul_0103 ferredoxin-dependent glutamate synthase; Belongs to the glutamate synthase family.
  
 
 0.952
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
  
 0.951
Dbac_2014
PFAM: aminotransferase class I and II; KEGG: aau:AAur_1949 aspartate aminotransferase.
   
 0.943
Dbac_2987
PFAM: aminotransferase class I and II; KEGG: dde:Dde_3596 L-aspartate aminotransferase.
   
 0.943
Dbac_3303
PFAM: aminotransferase class I and II; KEGG: dvl:Dvul_2140 aspartate aminotransferase.
   
 0.943
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
  
 0.941
Dbac_2819
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: dde:Dde_0104 L-glutamine synthetase.
  
 
 0.940
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
  
 
 0.938
Your Current Organism:
Desulfomicrobium baculatum
NCBI taxonomy Id: 525897
Other names: D. baculatum DSM 4028, Desulfomicrobium baculatum DSM 4028, Desulfomicrobium baculatum str. DSM 4028, Desulfomicrobium baculatum strain DSM 4028
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.