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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Taci_0187Phospholipase D/Transphosphatidylase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (526 aa)    
Predicted Functional Partners:
Taci_1661
PFAM: phosphatidylglycerophosphatase A; KEGG: dol:Dole_1265 phosphatidylglycerophosphatase A.
     
 0.916
Taci_0206
TIGRFAM: FeS cluster assembly scaffold protein NifU; PFAM: nitrogen-fixing NifU domain protein; KEGG: dol:Dole_0755 NifU domain-containing protein.
   
 
 0.873
Taci_0188
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: mms:mma_0278 glutamate dehydrogenase (NAD(P)+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.782
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.677
Taci_0189
PFAM: protein of unknown function DUF195; KEGG: mca:MCA0339 hypothetical protein.
       0.544
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.531
Taci_0640
TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3- phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: bha:BH2386 phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.489
ispF
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). Belongs to the IspF family. In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
     
 0.484
Taci_1451
KEGG: mgm:Mmc1_2383 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAC repeat-containing protein; PAS domain containing protein.
   
 
 0.462
Taci_0317
KEGG: glo:Glov_0049 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; nucleic acid binding OB-fold tRNA/helicase-type; SMART: metal-dependent phosphohydrolase HD region.
  
 
   0.405
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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