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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Taci_0233Transcriptional regulator, SARP family; SMART: AAA ATPase; KEGG: pol:Bpro_1406 transcriptional activator domain. (911 aa)    
Predicted Functional Partners:
Taci_0229
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase.
  
    0.804
hisC
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: maq:Maqu_1024 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
       0.773
Taci_0231
PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: dde:Dde_2206 prolyl-tRNA synthetase.
       0.773
Taci_0232
PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: bba:Bd1812 formimidoylglutamase; Belongs to the arginase family.
       0.773
Taci_1451
KEGG: mgm:Mmc1_2383 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
 0.623
hisI
TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: son:SO_2067 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.
       0.521
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
       0.521
hisA
PFAM: histidine biosynthesis protein; KEGG: pzu:PHZ_c0042 phosphoribosylformimino-5- aminoimidazole carboxamide ribotide isomerase.
       0.521
Taci_0225
TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; PFAM: glutamine amidotransferase class-I; CobB/CobQ domain protein glutamine amidotransferase; KEGG: predicted protein; K02501 glutamine amidotransferase.
       0.521
hisB
PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: hha:Hhal_1094 imidazoleglycerol-phosphate dehydratase.
       0.521
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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