Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (319 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.998
Taci_0246
TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: mca:MCA0017 adenosylmethionine--8-amino-7- oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.998
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
 
 0.953
Taci_0144
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sfu:Sfum_0841 biotin synthase.
  
  
  0.917
Taci_0029
KEGG: aba:Acid345_1822 aminotransferase; TIGRFAM: ornithine aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
  
 0.863
Taci_1652
KEGG: gbm:Gbem_0049 pyridoxal phosphate-dependent acyltransferase; TIGRFAM: pyridoxal phosphate-dependent acyltransferase; PFAM: aminotransferase class I and II; aminotransferase class-III; aromatic amino acid beta- eliminating lyase/threonine aldolase.
  
 0.853
Taci_0243
PFAM: BioY protein; KEGG: sfu:Sfum_1749 BioY protein.
  
  
 0.844
Taci_0450
PFAM: aminotransferase class-III; KEGG: bce:BC4127 acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
  
 0.647
Taci_0242
PFAM: glycoside hydrolase family 18; SMART: chitinase II; KEGG: wsu:WS0692 hypothetical protein.
       0.558
aroK
Shikimate kinase., 3-dehydroquinate synthase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
     
 0.470
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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