Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
psdPhosphatidylserine decarboxylase related protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (205 aa)    
Predicted Functional Partners:
Taci_0274
TIGRFAM: CDP-diacylglycerol/serine O- phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: wsu:WS0623 phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
 
 0.997
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.820
Taci_0640
TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3- phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: bha:BH2386 phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
   
 
 0.773
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
    
 0.738
Taci_0583
PFAM: beta-lactamase domain protein; KEGG: bcy:Bcer98_3294 metal-dependent hydrolase; Belongs to the UPF0173 family.
   
   0.703
Taci_0697
PFAM: band 7 protein; SMART: band 7 protein; KEGG: sat:SYN_02180 membrane protease subunit, stomatin/prohibitin -like protein.
    
   0.587
Taci_0271
PFAM: nitroreductase; KEGG: dvl:Dvul_0809 nitroreductase.
  
    0.540
Taci_0270
PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: aba:Acid345_0634 transcriptional regulator, AsnC family.
       0.518
Taci_0186
PFAM: metallophosphoesterase; KEGG: glo:Glov_2809 metallophosphoesterase.
 
     0.466
Taci_1079
DNA polymerase I; KEGG: bcy:Bcer98_3272 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; SMART: 5'-3' exonuclease; DNA-directed DNA polymerase; Helix-hairpin-helix domain protein class 2.
  
  
 0.425
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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