STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Taci_0274TIGRFAM: CDP-diacylglycerol/serine O- phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: wsu:WS0623 phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (242 aa)    
Predicted Functional Partners:
psd
Phosphatidylserine decarboxylase related protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
 
 
 0.997
Taci_0640
TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3- phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: bha:BH2386 phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
 
 0.949
Taci_0934
PFAM: phosphatidate cytidylyltransferase; KEGG: mxa:MXAN_2556 putative phosphatidate cytidylyltransferase; Belongs to the CDS family.
    
 0.933
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.900
Taci_0266
KEGG: bha:BH2497 L-serine dehydratase beta subunit; TIGRFAM: L-serine dehydratase, iron-sulfur- dependent, beta subunit; PFAM: serine dehydratase beta chain; amino acid- binding ACT domain protein.
     
  0.900
Taci_0267
KEGG: bcr:BCAH187_A4271 L-serine dehydratase, iron- sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur- dependent, alpha subunit; PFAM: serine dehydratase alpha chain.
     
  0.900
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
  0.900
Taci_1548
PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: ppw:PputW619_3319 L-serine ammonia-lyase.
     
  0.900
Taci_1720
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bcb:BCB4264_A2424 threonine ammonia-lyase, catabolic.
    
  0.900
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.825
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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