STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cutCCutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. (225 aa)    
Predicted Functional Partners:
Taci_0332
PFAM: phosphotransferase system lactose/cellobiose- specific IIB subunit; KEGG: bat:BAS5064 PTS system, cellobiose-specific IIB component.
 
     0.893
Taci_0329
PFAM: Ppx/GppA phosphatase; KEGG: acp:A2cp1_0693 Ppx/GppA phosphatase.
       0.773
Taci_0330
PFAM: Na+/Picotransporter; KEGG: rme:Rmet_1777 Na/Pi cotransporter II-related.
       0.773
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
    
   0.752
Taci_1459
TIGRFAM: PTS system, glucose-specific IIBC subunit; PTS system, glucose subfamily, IIA subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system EIIC; sugar- specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; KEGG: bha:BH0844 PTS system, glucose-specific enzyme II, A component.
     
 0.658
Taci_0328
Hypothetical protein.
       0.551
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.530
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
    0.503
Taci_0327
Hypothetical protein.
       0.482
nagB
Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
 
   
 0.451
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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