STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Taci_0441PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: mmw:Mmwyl1_4357 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Belongs to the 5'-nucleotidase family. (520 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.951
Taci_0564
Ribosylpyrimidine nucleosidase; PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: sfv:SFV_2237 ribonucleoside hydrolase 2.
 
 
 0.927
Taci_1021
KEGG: mxa:MXAN_5710 pyrimidine-nucleoside phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase domain; glycosyl transferase family 3; Glycosyl transferase, family 3-like.
 
  
 0.919
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.917
Taci_0457
PFAM: phosphoribosyltransferase; KEGG: dde:Dde_1506 xanthine-guanine phosphoribosyltransferase.
    
 0.916
Taci_1014
TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: sfu:Sfum_0660 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
 0.916
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.915
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.915
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.914
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
    
 0.914
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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