Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Taci_0538PFAM: UspA domain protein; KEGG: gur:Gura_3645 UspA domain-containing protein. (159 aa)    
Predicted Functional Partners:
Taci_0735
methylated-DNA/protein- cysteinemethyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
  
 0.670
Taci_0539
PFAM: 2-phosphosulfolactate phosphatase; KEGG: cbs:COXBURSA331_A1552 2-phosphosulfolactate phosphatase; Belongs to the ComB family.
       0.561
Taci_1451
KEGG: mgm:Mmc1_2383 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAC repeat-containing protein; PAS domain containing protein.
     
 0.550
hpf
Sigma 54 modulation protein/ribosomal protein S30EA; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
   
  
 0.515
Taci_0750
PFAM: CBS domain containing protein; Polynucleotide adenylyltransferase region; phosphoesterase RecJ domain protein; SMART: CBS domain containing protein; KEGG: gsu:GSU1581 polyA polymerase family protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
 
   
 0.474
Taci_1021
KEGG: mxa:MXAN_5710 pyrimidine-nucleoside phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase domain; glycosyl transferase family 3; Glycosyl transferase, family 3-like.
   
    0.455
Taci_1222
KEGG: afw:Anae109_4445 hypothetical protein.
   
  
 0.419
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.411
Taci_1738
KEGG: vvy:VV1157 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
     
 0.401
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.