STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Taci_0628PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: hypothetical protein. (363 aa)    
Predicted Functional Partners:
Taci_0627
PFAM: Heat shock protein 70; KEGG: bcr:BCAH187_A4447 chaperone protein DnaK.
 
 0.993
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.977
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
 
 0.954
Taci_0624
PFAM: ribosomal L11 methyltransferase; KEGG: dvm:DvMF_3155 ribosomal L11 methyltransferase.
  
  
 0.893
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.835
Taci_0496
PFAM: peptidase M16 domain protein; KEGG: saz:Sama_3596 pseudouridine synthase, Rsu; Belongs to the peptidase M16 family.
  
 
 0.813
rplQ
TIGRFAM: ribosomal protein L17; PFAM: ribosomal protein L17; KEGG: cti:RALTA_A2917 50S ribosomal subunit protein L17.
  
 
 0.787
Taci_1557
PFAM: major intrinsic protein; KEGG: azc:AZC_2711 glycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
 
 0.785
Taci_0625
Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
  
   0.774
Taci_0176
TIGRFAM: redox-active disulfide protein 2; KEGG: dps:DP0946 hypothetical protein.
    
 0.773
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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