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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (450 aa)    
Predicted Functional Partners:
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
  
 0.840
Taci_0692
PFAM: Fe-S cluster domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: glo:Glov_0467 transcriptional regulator, Fis family.
       0.774
Taci_0693
HPr kinase.
       0.774
Taci_0694
PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: ank:AnaeK_1370 PHP domain protein.
       0.774
Taci_0748
PFAM: UvrD/REP helicase; KEGG: bha:BH0648 ATP-dependent DNA helicase.
   
  
 0.724
Taci_0696
PFAM: protein of unknown function DUF107; KEGG: sus:Acid_1498 nodulation efficiency protein NfeD.
       0.711
Taci_0697
PFAM: band 7 protein; SMART: band 7 protein; KEGG: sat:SYN_02180 membrane protease subunit, stomatin/prohibitin -like protein.
       0.711
ispF
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). Belongs to the IspF family. In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
  
  
 0.652
Taci_1079
DNA polymerase I; KEGG: bcy:Bcer98_3272 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; SMART: 5'-3' exonuclease; DNA-directed DNA polymerase; Helix-hairpin-helix domain protein class 2.
     
 0.647
Taci_0691
Putative anti-sigma regulatory factor, serine/threonine protein kinase; KEGG: bsu:BSU04690 switch protein/serine-threonine kinase.
     
 0.638
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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