Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Taci_0717Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: amc:MADE_03339 response regulator consisting of a CheY-like receiver domain and a winged-helix DNA- binding domain. (226 aa)    
Predicted Functional Partners:
Taci_1451
KEGG: mgm:Mmc1_2383 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; Hpt domain protein; PAC repeat-containing protein; PAS domain containing protein.
 
 
0.969
Taci_1738
KEGG: vvy:VV1157 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
 
 
 0.965
Taci_0716
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sfu:Sfum_2006 integral membrane sensor signal transduction histidine kinase.
 
 0.962
Taci_1372
KEGG: bvi:Bcep1808_5667 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; CHASE4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAC repeat-containing protein; histidine kinase HAMP region domain protein; PAS domain containing protein.
 
 
 0.954
Taci_1376
PAS/PAC sensor signal transduction histidine kinase; KEGG: dar:Daro_0420 PAS; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold-3 domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein.
 
 
 0.911
Taci_0089
PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: mgm:Mmc1_1492 multi-sensor signal transduction histidine kinase.
 
 
 0.852
Taci_0357
CheA signal transduction histidine kinase; PFAM: response regulator receiver; CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; SMART: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; KEGG: gme:Gmet_2710 CheA signal transduction histidine kinase.
  
 
 0.834
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.786
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.782
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.774
Your Current Organism:
Thermanaerovibrio acidaminovorans
NCBI taxonomy Id: 525903
Other names: T. acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans DSM 6589, Thermanaerovibrio acidaminovorans str. DSM 6589, Thermanaerovibrio acidaminovorans strain DSM 6589
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